Bo Xian

Associate Researcher
Email: bioxian(at)163.com

Experience

• 2011.6 - Present, Han Lab, PICB, SIBS, CAS.
• 2005.12 - 2011.6, Han Lab, Institute of Genetics and Developmental Biology, CAS.
• 2004.9 - 2005.11, Hu Lab, Institute of Genetics and Developmental Biology, CAS.
• 2003.9 - 2004.8, 2003508, Graduate University of CAS.
• 1999.9 - 2003.7, Beijing Forestry University.

Research Focus

My research interests are to systematically investigate the aging process and screen anti-aging natural compounds by applying automatic microfluidic technology on C.elegans.

Publications

• Gao S, Chen WY, Zeng YX, Jing HM, Zhang N, Flavel M, Jois M, Han JD, Xian B*, Li GJ*. Classification and prediction of toxicity of chemicals using an automated phenotypic profiling of Caenorhabditis elegans. BMC Pharmacology and Toxicology. Apr 2018,18;19(1):18.
• Chen WY, Liao B, Li W, Dong X, Flavel M, Jois M, Li G, Xian B. Segmenting Microscopy Images of Multi-Well Plates Based on Image Contrast. Microsc Microanal. Oct 2017;23(5):932-937.
• Flavel MR, Mechler A, Shahmiri M, Mathews ER, Xian B, Gao S, Luo J, Tegegne S, Doneski C, Jois M. Growth of Caenorhabditis elegans in Defined Media Is Dependent on Presence of Particulate Matter. G3 (Bethesda), Dec, 2017 pii: g3.300325.
• Hou L, Wang D, Cheng H, Xian B, Han JD. Systems Approaches to Understanding Aging. Handbook of the Biology of Aging (Eighth Edition). Dec,2016, Pages 241–261, DOI: 10.1016/B978-0-12-411596-5.00008-3.
• Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Tocchi A, Xian B, et al. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell. Jul, 2013.
• Zhang H, Zhang YW, Chen Y, Huang X, Zhou F, Wang W, Xian B, Zhang X, Masliah E, Chen Q, Han JD, Bu G, Reed JC, Liao FF, Chen YG, Xu H*. Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration. J Neurosci. 32(44):15565-76.2012.

Personal Show

• Hobbies: Photograhy, Pool, Fishing...